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Study Guide: CLEP

Study resources to prepare for College-Level Examination Program® (CLEP) exams.

What's on the test?

Overview

The Biology exam covers the broad field of the biological sciences, organized into three major areas: molecular and cellular biology, organismal biology, and population biology.

# of Questions Time 
115 90 minutes

Knowledge and Skills Required

  • Knowledge of facts, principles, and processes of biology
  • Understanding the means by which information is collected, how it is interpreted, how one hypothesizes from available information, and how one draws conclusions and makes further predictions
  • Understanding that science is a human endeavor with social consequences

Score Information

ACE Recommendation for Biology

Credit-granting Score Semester Hours
50 3
Note: Each institution reserves the right to set its own credit-granting policy, which may differ from the American Council on Education (ACE). Contact your the TSTC testing center to find out the score required for credit and the number of credit hours granted.

The subject matter of the Biology exam is drawn from the following topics. The percentages next to the main topics indicate the approximate percentage of exam questions on that topic.

Molecular and Cellular Biology (33%)

Chemical composition of organisms
  • Simple chemical reactions and bonds
  • Properties of water
  • Chemical structure of carbohydrates, lipids, proteins, and nucleic acids
  • Origin of life
Cells
  • Structure and function of cell organelles
  • Properties of cell membranes
  • Comparison of prokaryotic and eukaryotic cells
Enzymes
  • Enzyme-substrate complex
  • Roles of coenzymes
  • Inorganic cofactors
  • Inhibition and regulation
Energy transformations
  • Glycolysis, respiration, and anaerobic pathways
  • Photosynthesis
Cell division
  • Structure of chromosomes
  • Mitosis, meiosis, and cytokinesis in plants and animals
Chemical nature of the gene
  • Watson-Crick model of nucleic acids
  • DNA replication
  • Mutations
  • Control of protein synthesis: transcription, translation, and posttranscriptional processing
  • Structural and regulatory genes
  • Transformation
  • Viruses

Organismal Biology (34%)

Structure and function in plants with emphasis on angiosperms
  • Root, stem, leaf, flower, seed, and fruit
  • Water and mineral absorption and transport
  • Food translocation and storage
Plant reproduction and development
  • Alternation of generations in ferns, conifers, and flowering plants
  • Gamete formation and fertilization
  • Growth and development: hormonal control
  • Tropisms and photoperiodicity
Structure and function in animals with emphasis on vertebrates
  • Major systems (e.g., digestive, gas exchange, skeletal, nervous, circulatory, excretory, and immune)
  • Homeostatic mechanisms
  • Hormonal control in homeostasis and reproduction
Animal reproduction and development
  • Gamete formation and fertilization
  • Cleavage, gastrulation, germ layer formation, and differentiation of organ systems
  • Experimental analysis of vertebrate development
  • Extraembryonic membranes of vertebrates
  • Formation and function of the mammalian placenta
  • Blood circulation in the human embryo
Principles of heredity
  • Mendelian inheritance (dominance, segregation, independent assortment)
  • Chromosomal basis of inheritance
  • Linkage, including sex-linked
  • Polygenic inheritance (height, skin color, etc.)
  • Multiple alleles (human blood groups)

Population Biology (33%)

Principles of ecology
  • Energy flow and productivity in ecosystems
  • Biogeochemical cycles
  • Population growth and regulation (natality, mortality, competition, migration, density, r- and K-selection)
  • Community structure, growth, and regulation (major biomes and succession)
  • Habitat (biotic and abiotic factors)
  • Concept of niche
  • Island biogeography
  • Evolutionary ecology (life history strategies, altruism, and kin selection)
Principles of evolution
  • History of evolutionary concepts
  • Concepts of natural selection (differential reproduction, mutation, Hardy-Weinberg equilibrium, speciation, and punctuated equilibrium)
  • Adaptive radiation
  • Major features of plant and animal evolution
  • Concepts of homology and analogy
  • Convergence, extinction, balanced polymorphism, and genetic drift
  • Classification of living organisms
  • Evolutionary history of humans
Principles of behavior
  • Stereotyped and learned social behavior
  • Societies (insects, birds, and primates)
Social biology
  • Human population growth (age composition, birth and fertility rates, and theory of demographic transition)
  • Human intervention in the natural world (management of resources, and environmental pollution)
  • Biomedical progress (control of human reproduction, and genetic engineering)

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